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KMID : 1188320130070030303
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Gut and Liver
2013 Volume.7 No. 3 p.303 ~ p.310
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Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
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Joo Young-Eun
Park Hyun-Kyung
Myung Dae-Seong
Baik Gwang-Ho
Shin Jeong-Eun
Seo Geom-Seog
Kim Gwang-Ha
Kim Heung-Up
Kim Hyun-Young
Cho Sung-Il
Kim Na-Young
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Abstract
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Background/Aims:Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions.
Methods:In total, 4,023 subjects were enrolled at eight hospitals in Korea. AG and IM were diagnosed by endoscopy. Helicobacter pylori immunoglobulin G antibodies were measured.
Results:The prevalences of endoscopic AG and IM were 40.7% and 12.5%. In a multivariate analysis, the risk factors for AG were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, IM, and education below the college level (odds ratio [OR], 2.55, 5.00, 1.38, 1.41, 4.29, and 1.35, respectively). The risk factors for IM were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, AG, having relatives with gastric cancer, education below the college level and consumption of dairy products (OR, 3.16, 3.25, 1.88, 2.17, 3.68, 1.48, 1.47, and 1.40, respectively).
Conclusions:A nationwide survey regarding the prevalence of endoscopic AG and IM and their risk factors in Korea supports the hypothesis that endoscopic diagnosis of these premalignant lesions could be helpful to describe a group at high risk for gastric cancer
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KEYWORD
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Atrophic gastritis, Intestinal metaplasia, Prevalence, Risk factors, Endoscopy
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